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Novel Virulence Role of Pneumococcal NanA in Host Inflammation and Cell Death Through the Activation of Inflammasome and the Caspase Pathway

Streptococcus pneumoniae is one of most deadly Gram-positive bacterium that causes significant mortality and morbidity worldwide. Intense inflammation and cytotoxicity is a hallmark of invasive pneumococcal disease. Pneumococcal NanA has been shown to exaggerate the production of inflammatory cytoki...

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Detalles Bibliográficos
Autores principales: Tseng, Yu-Wen, Chang, Chun-Chi, Chang, Yung-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991587/
https://www.ncbi.nlm.nih.gov/pubmed/33777832
http://dx.doi.org/10.3389/fcimb.2021.613195