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Long read, isoform aware sequencing of mouse nucleus accumbens after chronic cocaine treatment

To better understand the full-length transcriptome of the nucleus accumbens (NAc)—a key brain reward region—in chronic cocaine treatment, we perform the first single molecule, long-read sequencing analysis using the Iso-seq method to detect 42,114 unique transcripts from mouse NAc polyadenylated RNA...

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Detalles Bibliográficos
Autores principales: Estill, Molly, Ribeiro, Efrain, Francoeur, Nancy J., Smith, Melissa L., Sebra, Robert, Yeh, Szu-Ying, Cunningham, Ashley M., Nestler, Eric J., Shen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991652/
https://www.ncbi.nlm.nih.gov/pubmed/33762610
http://dx.doi.org/10.1038/s41598-021-86068-7