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Long read, isoform aware sequencing of mouse nucleus accumbens after chronic cocaine treatment
To better understand the full-length transcriptome of the nucleus accumbens (NAc)—a key brain reward region—in chronic cocaine treatment, we perform the first single molecule, long-read sequencing analysis using the Iso-seq method to detect 42,114 unique transcripts from mouse NAc polyadenylated RNA...
Autores principales: | Estill, Molly, Ribeiro, Efrain, Francoeur, Nancy J., Smith, Melissa L., Sebra, Robert, Yeh, Szu-Ying, Cunningham, Ashley M., Nestler, Eric J., Shen, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991652/ https://www.ncbi.nlm.nih.gov/pubmed/33762610 http://dx.doi.org/10.1038/s41598-021-86068-7 |
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