Comparative Analysis of BTK Inhibitors and Mechanisms Underlying Adverse Effects

The cytoplasmic protein-tyrosine kinase BTK plays an essential role for differentiation and survival of B-lineage cells and, hence, represents a suitable drug target. The number of BTK inhibitors (BTKis) in the clinic has increased considerably and currently amounts to at least 22. First-in-class wa...

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Detalles Bibliográficos
Autores principales: Estupiñán, H. Yesid, Berglöf, Anna, Zain, Rula, Smith, C. I. Edvard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991787/
https://www.ncbi.nlm.nih.gov/pubmed/33777941
http://dx.doi.org/10.3389/fcell.2021.630942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991787/
https://www.ncbi.nlm.nih.gov/pubmed/33777941
http://dx.doi.org/10.3389/fcell.2021.630942

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