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Clinicopathological characteristics and mutational profile of KRAS and NRAS in Tunisian patients with sporadic colorectal cancer

BACKGROUND/AIM: Colorectal cancer (CRC) is a major public health problem worldwide and in Tunisia due to its increasing rate of incidence. KRAS and NRAS mutations have become a pivotal part of CRC diagnosis, given their association to treatment resistance with antiepidermal growth factor receptor (E...

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Detalles Bibliográficos
Autores principales: OUNISSI, Donia, WESLATI, Marwa, BOUGHRIBA, Rahma, HAZGUI, Meriam, BOURAOUI, Saadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991861/
https://www.ncbi.nlm.nih.gov/pubmed/32892548
http://dx.doi.org/10.3906/sag-2003-42