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The importance of histological patterns on PD-L1 staining heterogeneity: Should we use pattern-based approach for selecting tumor samples for PD-L1 testing in lung adenocarcinomas?

BACKGROUND/AIM: Programmed death ligand-1 (PD-L1) is a predictive marker for immunotherapeutic agents. However, heterogeneous staining of PD-L1 can cause false-negative results. The aim of this study is to evaluate the importance of histological patterns on PD-L1 staining heterogeneity in lung adeno...

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Detalles Bibliográficos
Autores principales: BULUTAY, Pınar, FIRAT, Pınar, ZEREN, Handan, ERUS, Suat, TANJU, Serhan, DİLEGE, Şükrü
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7991888/
https://www.ncbi.nlm.nih.gov/pubmed/33155793
http://dx.doi.org/10.3906/sag-2004-61