Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms

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[Image: see text] Severe acute respiratory coronavirus 2 (SARS-CoV-2) is a newly identified virus that has resulted in over 2.5 million deaths globally and over 116 million cases globally in March, 2021. Small-molecule inhibitors that reverse disease severity have proven difficult to discover. One o...

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Detalles Bibliográficos
Autores principales: Puhl, Ana C., Fritch, Ethan J., Lane, Thomas R., Tse, Longping V., Yount, Boyd L., Sacramento, Carolina Q., Fintelman-Rodrigues, Natalia, Tavella, Tatyana Almeida, Maranhão Costa, Fabio Trindade, Weston, Stuart, Logue, James, Frieman, Matthew, Premkumar, Lakshmanane, Pearce, Kenneth H., Hurst, Brett L., Andrade, Carolina Horta, Levi, James A., Johnson, Nicole J., Kisthardt, Samantha C., Scholle, Frank, Souza, Thiago Moreno L., Moorman, Nathaniel John, Baric, Ralph S., Madrid, Peter B., Ekins, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992063/
https://www.ncbi.nlm.nih.gov/pubmed/33778258
http://dx.doi.org/10.1021/acsomega.0c05996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992063/
https://www.ncbi.nlm.nih.gov/pubmed/33778258
http://dx.doi.org/10.1021/acsomega.0c05996

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