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Optimization, Characterization and in vivo Evaluation of Paclitaxel-Loaded Folate-Conjugated Superparamagnetic Iron Oxide Nanoparticles

BACKGROUND: Paclitaxel (PTX) has interesting anticancer activity. However, it is insoluble in water, which seriously hinders its use in clinical. Superparamagnetic iron oxide nanoparticles (SPIONs) are used as an ideal drug delivery system. Therefore, we proposed a folic acid (FA) targeting drug-loa...

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Detalles Bibliográficos
Autores principales: Gui, Gang, Fan, Ziqi, Ning, Yihuan, Yuan, Cancan, Zhang, Baolin, Xu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992116/
https://www.ncbi.nlm.nih.gov/pubmed/33776433
http://dx.doi.org/10.2147/IJN.S287434