Genetic Fusion of Transacting Activator of Transcription Peptide to Cyclized Green Fluorescence Protein Improves Stability, Intracellular Delivery, and Tumor Retention

[Image: see text] Therapeutic proteins such as enzymes, hormones, and cytokines suffer from poor stability, inefficient cellular penetration, and rapid clearance from circulation. Conjugation with polymers (such as poly(ethylene glycol)) and fusion with long-acting proteins (such as albumin and Fc f...

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Detalles Bibliográficos
Autores principales: Shi, Jianquan, Hu, Jin, Yuan, Yeshuang, Zhang, Bo, Guo, Wenting, Wu, Yuanhao, Jiang, Lingjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992142/
https://www.ncbi.nlm.nih.gov/pubmed/33778304
http://dx.doi.org/10.1021/acsomega.1c00532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992142/
https://www.ncbi.nlm.nih.gov/pubmed/33778304
http://dx.doi.org/10.1021/acsomega.1c00532

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