TBMT-01. HYPERPOLARIZED δ-[1-(13)C]GLUCONOLACTONE MONITORS TERT-INDUCED ELEVATION IN PENTOSE PHOSPHATE PATHWAY FLUX IN BRAIN TUMORS IN VIVO

Telomerase reverse transcriptase (TERT) expression is essential for tumor proliferation and is an attractive therapeutic target for gliomas. TERT expression has previously been shown to enhance glucose flux via the pentose phosphate pathway (PPP) in low grade gliomas expressing TERT. Hyperpolarized...

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Detalles Bibliográficos
Autores principales: Batsios, Georgios, Viswanath, Pavithra, Taglang, Celine, Flavell, Robert, Costello, Joseph, Pieper, Russell O, Larson, Peder, Ronen, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992198/
http://dx.doi.org/10.1093/noajnl/vdab024.083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992198/
http://dx.doi.org/10.1093/noajnl/vdab024.083

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