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FSMP-06. IN VIVO MONITORING OF LDHA EXPRESSION IN GLIOBLASTOMA USING QUANTITATIVE EXCHANGED-LABEL TURNOVER (1)H MRS TECHNIQUE

Most cancers, including glioblastomas (GBMs), rely extensively on glycolysis to support growth, proliferation, and survival. A hallmark of this elevated glycolysis is overexpression of Lactate dehydrogenase-A (LDHA) protein leading to increased uptake of glucose and overproduction of lactate. Variou...

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Detalles Bibliográficos
Autores principales: Bagga, Puneet, Rich, Laurie, Haris, Mohammad, Wilson, Neil, Schnall, Mitch, Detre, John, Patay, Zoltan, Gajjar, Amar, Akers, Walter, Steinberg, Jeffrey, Krenciute, Giedre, Baker, Suzanne, Reddy, Ravinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992206/
http://dx.doi.org/10.1093/noajnl/vdab024.070