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FSMP-06. IN VIVO MONITORING OF LDHA EXPRESSION IN GLIOBLASTOMA USING QUANTITATIVE EXCHANGED-LABEL TURNOVER (1)H MRS TECHNIQUE
Most cancers, including glioblastomas (GBMs), rely extensively on glycolysis to support growth, proliferation, and survival. A hallmark of this elevated glycolysis is overexpression of Lactate dehydrogenase-A (LDHA) protein leading to increased uptake of glucose and overproduction of lactate. Variou...
Autores principales: | Bagga, Puneet, Rich, Laurie, Haris, Mohammad, Wilson, Neil, Schnall, Mitch, Detre, John, Patay, Zoltan, Gajjar, Amar, Akers, Walter, Steinberg, Jeffrey, Krenciute, Giedre, Baker, Suzanne, Reddy, Ravinder |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992206/ http://dx.doi.org/10.1093/noajnl/vdab024.070 |
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