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DDRE-13. INHIBITION OF EXTRACELLULAR CARBONIC ANHYDRASES INHIBITS GLIOBLASTOMA CELL INVASION

OBJECTIVE: Malignant gliomas metabolize glucose preferably by glycolysis which is in accordance with the Warburg effect. This induces a high demand of glucose combined with a significant lactic acid load. The hypoxia-inducible carbonic anhydrase (CA) IX has been shown to moderate the extrusion of hy...

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Detalles Bibliográficos
Autores principales: Proescholdt, Martin, Zhenwei, Qiu, Annette, Lohmeier, Nils-Ole, Schmidt, Marsha, Merrill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992214/
http://dx.doi.org/10.1093/noajnl/vdab024.035