DDRE-20. TARGETING SPHINGOLIPID PATHWAY REVEALS VULNERABILITY IN IDH1(MUT) GLIOMA

BACKGROUND: While central carbon metabolism has been studied extensively in cancer, lipidomic research is sparse. Sphingolipids participate in cellular functions including secondary messengers, lymphocyte trafficking, inflammation, angiogenesis, migration, proliferation, necrosis and apoptosis, thus...

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Detalles Bibliográficos
Autores principales: Dowdy, Tyrone, Zhang, Lumin, Celiku, Orieta, Movva, Sriya, Ruiz-Rodado, Victor, Lita, Adrian, Larion, Mioara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992217/
http://dx.doi.org/10.1093/noajnl/vdab024.042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992217/
http://dx.doi.org/10.1093/noajnl/vdab024.042

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