FSMP-07. CYSTATHIONINE-Γ-LYASE DRIVES ANTIOXIDANT DEFENSE IN CYSTEINE-RESTRICTED IDH1 MUTANT ASTROCYTOMAS

Mutations in isocitrate dehydrogenase 1 or 2 (IDH1/2) define glioma subtypes and are considered primary events in gliomagenesis, impacting tumor epigenetics and metabolism. IDH enzymes are crucial for the generation of reducing potential, yet the impact of the mutation on the cellular antioxidant sy...

Descripción completa

Detalles Bibliográficos
Autores principales: Cano-Galiano, Andrés, Oudin, Anais, Fack, Fred, Allega, Maria-Francesca, Sumpton, David, Martinez-Garcia, Elena, Dittmar, Gunnar, Hau, Ann-Christin, Herold-Mende, Christel, Bjerkvig, Rolf, Meiser, Johannes, Tardito, Saverio, Niclou, Simone P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992224/
http://dx.doi.org/10.1093/noajnl/vdab024.071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992224/
http://dx.doi.org/10.1093/noajnl/vdab024.071

Ejemplares similares