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FSMP-11. TARGETING CHOLESTEROL HOMEOSTASIS DYSREGULATION FOR THE TREATMENT OF GLIOBLASTOMA
Dysregulated cholesterol metabolism is a hallmark of many cancers, including glioblastoma (GBM), but its role in disease progression is not well understood. Here, we identified cholesterol 24-hydroxylase (CYP46A1), a brain-specific enzyme responsible for elimination of cholesterol through conversion...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992230/ http://dx.doi.org/10.1093/noajnl/vdab024.075 |