DDRE-28. MECHANISTIC AND THERAPEUTIC LINKS BETWEEN PURINE BIOSYNTHESIS AND DNA DAMAGE IN GLIOBLASTOMA

Glioblastoma (GBM) is the most common and aggressive adult brain cancer. Radiation therapy (RT) is a critical treatment modality, and development of RT resistance is the predominant cause of recurrence and mortality in GBM patients. Using cell line models as well as patient-derived xenografts and ne...

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Detalles Bibliográficos
Autores principales: Scott, Andrew, Zhou, Weihua, Wilder-Romans, Kari, Feng, Jiane, Wu, Zhe, Andren, Anthony, Zhang, Li, Sajjakulnukit, Peter, Kachman, Maureen, Umemura, Yoshie, Schmitt, Melanie, Qi, Nathan, Lawrence, Theodore, Lyssiotis, Costas, Wahl, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992234/
http://dx.doi.org/10.1093/noajnl/vdab024.050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992234/
http://dx.doi.org/10.1093/noajnl/vdab024.050

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