BIMG-18. ELEVATED CYSTATHIONINE IN MEDULLOBLASTOMA DEMONSTRATES TUMOR-SPECIFIC METHIONINE METABOLISM

We investigated tumor-specific metabolism medulloblastoma using a non-biased MS-imaging screen and identified a pattern of methionine flux that may present a therapeutic opportunity. We studied brain tumors that form in mice genetically engineered to develop Sonic Hedgehog (SHH)-driven medulloblasto...

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Detalles Bibliográficos
Autores principales: Tikunov, Andrey, Rosen, Elias, Babcock, Ben, Weir, Seth, Parnham, Stuart, Macdonald, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992236/
http://dx.doi.org/10.1093/noajnl/vdab024.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992236/
http://dx.doi.org/10.1093/noajnl/vdab024.017

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