BIMG-02. IMAGING IMMORTALITY: TERT EXPRESSION ALTERS GLUCOSE METABOLISM IN LOW-GRADE GLIOMAS IN A MANNER THAT CAN BE LEVERAGED FOR NONINVASIVE METABOLIC IMAGING

Telomerase reverse transcriptase (TERT) is essential for tumor immortality and uncontrolled proliferation, including in low-grade oligodendrogliomas (LGOGs). Since it is silenced in somatic cells, TERT is also a therapeutic target. Non-invasive imaging of TERT can differentiate tumor from normal bra...

Descripción completa

Detalles Bibliográficos
Autores principales: Viswanath, Pavithra, Batsios, Georgios, Gillespie, Anne Marie, Luchman, Hema Artee, Costello, Joseph, Pieper, Russell, Ronen, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992259/
http://dx.doi.org/10.1093/noajnl/vdab024.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992259/
http://dx.doi.org/10.1093/noajnl/vdab024.001

Ejemplares similares