Functional analysis of SARS-CoV-2 proteins in Drosophila identifies Orf6-induced pathogenic effects with Selinexor as an effective treatment

BACKGROUND: SARS-CoV-2 causes COVID-19 with a widely diverse disease profile that affects many different tissues. The mechanisms underlying its pathogenicity in host organisms remain unclear. Animal models for studying the pathogenicity of SARS-CoV-2 proteins are lacking. METHODS: Using bioinformati...

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Detalles Bibliográficos
Autores principales: Zhu, Jun-yi, Lee, Jin-Gu, van de Leemput, Joyce, Lee, Hangnoh, Han, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992514/
https://www.ncbi.nlm.nih.gov/pubmed/33766136
http://dx.doi.org/10.1186/s13578-021-00567-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992514/
https://www.ncbi.nlm.nih.gov/pubmed/33766136
http://dx.doi.org/10.1186/s13578-021-00567-8

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