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Epigenetic Regulation of Filaggrin Gene Expression in Human Epidermal Keratinocytes

BACKGROUND: Loss-of-function mutations in the filaggrin gene (FLG), which encodes an epidermal protein crucial for the formation of a functional skin barrier, have been identified as a major predisposing factor in the etiopathogenesis of atopic dermatitis (AD). Recent reports of relatively low frequ...

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Detalles Bibliográficos
Autores principales: Lee, Jaehyouk, Jang, Ara, Seo, Seong Jun, Myung, Soon Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992546/
https://www.ncbi.nlm.nih.gov/pubmed/33911723
http://dx.doi.org/10.5021/ad.2020.32.2.122