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The Significance of NOTCH Pathway in the Development of Fibrosis in Systemic Sclerosis

Systemic sclerosis (SSc) is an autoimmune disorder characterized by the fibrosis of skin, heart, lung, and kidney as well. Excessive activation of fibroblasts is associated with higher expression of Notch1 and/or Notch3 genes. The constitutive expression of NOTCH genes was described in epithelial ce...

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Detalles Bibliográficos
Autores principales: Zmorzyński, Szymon, Styk, Wojciech, Filip, Agata Anna, Krasowska, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992759/
https://www.ncbi.nlm.nih.gov/pubmed/33911613
http://dx.doi.org/10.5021/ad.2019.31.4.365