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Perspective of mesenchymal transformation in glioblastoma

Despite aggressive multimodal treatment, glioblastoma (GBM), a grade IV primary brain tumor, still portends a poor prognosis with a median overall survival of 12–16 months. The complexity of GBM treatment mainly lies in the inter- and intra-tumoral heterogeneity, which largely contributes to the tre...

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Detalles Bibliográficos
Autores principales: Kim, Yona, Varn, Frederick S., Park, Sung-Hye, Yoon, Byung Woo, Park, Hye Ran, Lee, Charles, Verhaak, Roel G. W., Paek, Sun Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992784/
https://www.ncbi.nlm.nih.gov/pubmed/33762019
http://dx.doi.org/10.1186/s40478-021-01151-4