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Chronically altered NMDAR signaling in epilepsy mediates comorbid depression

Depression is the most common psychiatric comorbidity of epilepsy. However, the molecular pathways underlying this association remain unclear. The NMDA receptor (NMDAR) may play a role in this association, as its downstream signaling has been shown to undergo long-term changes following excitotoxic...

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Detalles Bibliográficos
Autores principales: Sadeghi, Mohammad Amin, Hemmati, Sara, Mohammadi, Sina, Yousefi-Manesh, Hasan, Vafaei, Ali, Zare, Meysam, Dehpour, Ahmad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992813/
https://www.ncbi.nlm.nih.gov/pubmed/33762011
http://dx.doi.org/10.1186/s40478-021-01153-2