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Molecular remission after combination therapy with blinatumomab and ponatinib with relapsed/refractory Philadelphia chromosome-positive acute lymphocytic leukemia: two case reports

BACKGROUND: The outcomes of Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) can improve with allogeneic hematopoietic stem cell transplantation (HSCT) during the first complete remission after treatment with a tyrosine kinase inhibitor (TKI) combined with chemotherapy. Howe...

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Detalles Bibliográficos
Autores principales: Yuda, Junichiro, Yamauchi, Nobuhiko, Kuzume, Ayumi, Guo, Yong-Mei, Sato, Nobue, Minami, Yosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992866/
https://www.ncbi.nlm.nih.gov/pubmed/33762010
http://dx.doi.org/10.1186/s13256-021-02771-z