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Lipoxin A4 protects against paraquat-induced acute lung injury by inhibiting the TLR4/MyD88-mediated activation of the NF-κB and PI3K/AKT pathways

Paraquat (PQ) causes serious oxidative stress and inflammatory responses, particularly to the lungs. Since lipoxin A4 (LXA4) functions as an anti-inflammatory mediator, the present study aimed to explore its effects on PQ-induced acute lung injury (ALI) and to elucidate the possible underlying mecha...

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Detalles Bibliográficos
Autores principales: Li, Yuhua, Wang, Na, Ma, Zhongliang, Wang, Yunwen, Yuan, Yuan, Zhong, Zhitao, Hong, Yi, Zhao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992923/
https://www.ncbi.nlm.nih.gov/pubmed/33760150
http://dx.doi.org/10.3892/ijmm.2021.4919