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Lipoxin A4 protects against paraquat-induced acute lung injury by inhibiting the TLR4/MyD88-mediated activation of the NF-κB and PI3K/AKT pathways
Paraquat (PQ) causes serious oxidative stress and inflammatory responses, particularly to the lungs. Since lipoxin A4 (LXA4) functions as an anti-inflammatory mediator, the present study aimed to explore its effects on PQ-induced acute lung injury (ALI) and to elucidate the possible underlying mecha...
Autores principales: | Li, Yuhua, Wang, Na, Ma, Zhongliang, Wang, Yunwen, Yuan, Yuan, Zhong, Zhitao, Hong, Yi, Zhao, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992923/ https://www.ncbi.nlm.nih.gov/pubmed/33760150 http://dx.doi.org/10.3892/ijmm.2021.4919 |
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