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GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase

BACKGROUND: Fructose is an abundant source of carbon and energy for cells to use for metabolism, but only certain cell types use fructose to proliferate. Tumor cells that acquire the ability to metabolize fructose have a fitness advantage over their neighboring cells, but the proteins that mediate f...

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Detalles Bibliográficos
Autores principales: Liang, Roger J., Taylor, Samuel, Nahiyaan, Navid, Song, Junho, Murphy, Charles J., Dantas, Ezequiel, Cheng, Shuyuan, Hsu, Ting-Wei, Ramsamooj, Shakti, Grover, Rahul, Hwang, Seo-Kyoung, Ngo, Bryan, Cantley, Lewis C., Rhee, Kyu Y., Goncalves, Marcus D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992954/
https://www.ncbi.nlm.nih.gov/pubmed/33762003
http://dx.doi.org/10.1186/s40170-021-00246-9