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GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase
BACKGROUND: Fructose is an abundant source of carbon and energy for cells to use for metabolism, but only certain cell types use fructose to proliferate. Tumor cells that acquire the ability to metabolize fructose have a fitness advantage over their neighboring cells, but the proteins that mediate f...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992954/ https://www.ncbi.nlm.nih.gov/pubmed/33762003 http://dx.doi.org/10.1186/s40170-021-00246-9 |