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NRF2 is required for structural and metabolic maturation of human induced pluripotent stem cell-derived ardiomyocytes

BACKGROUND: Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) hold great promise for regenerative medicine and in drugs screening. Despite displaying key cardiomyocyte phenotypic characteristics, they more closely resemble fetal/neonatal cardiomyocytes and are still immature; th...

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Detalles Bibliográficos
Autores principales: Zhang, Xinyuan, Ye, Liang, Xu, Hao, Zhou, Qin, Tan, Bin, Yi, Qin, Yan, Liang, Xie, Min, Zhang, Yin, Tian, Jie, Zhu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992990/
https://www.ncbi.nlm.nih.gov/pubmed/33762018
http://dx.doi.org/10.1186/s13287-021-02264-2