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NRF2 is required for structural and metabolic maturation of human induced pluripotent stem cell-derived ardiomyocytes
BACKGROUND: Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) hold great promise for regenerative medicine and in drugs screening. Despite displaying key cardiomyocyte phenotypic characteristics, they more closely resemble fetal/neonatal cardiomyocytes and are still immature; th...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992990/ https://www.ncbi.nlm.nih.gov/pubmed/33762018 http://dx.doi.org/10.1186/s13287-021-02264-2 |