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Increased sCD163 and sCD14 Plasmatic Levels and Depletion of Peripheral Blood Pro-Inflammatory Monocytes, Myeloid and Plasmacytoid Dendritic Cells in Patients With Severe COVID-19 Pneumonia

BACKGROUND: Emerging evidence argues that monocytes, circulating innate immune cells, are principal players in COVID-19 pneumonia. The study aimed to investigate the role of soluble (s)CD163 and sCD14 plasmatic levels in predicting disease severity and characterize peripheral blood monocytes and den...

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Detalles Bibliográficos
Autores principales: Zingaropoli, Maria Antonella, Nijhawan, Parni, Carraro, Anna, Pasculli, Patrizia, Zuccalà, Paola, Perri, Valentina, Marocco, Raffaella, Kertusha, Blerta, Siccardi, Guido, Del Borgo, Cosmo, Curtolo, Ambrogio, Ajassa, Camilla, Iannetta, Marco, Ciardi, Maria Rosa, Mastroianni, Claudio Maria, Lichtner, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993197/
https://www.ncbi.nlm.nih.gov/pubmed/33777012
http://dx.doi.org/10.3389/fimmu.2021.627548