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In Silico Approach to Predict Severe Cutaneous Adverse Reactions Using the Japanese Adverse Drug Event Report Database

Severe cutaneous adverse reactions (SCARs), such as Stevens–Johnson syndrome/toxic epidermal necrolysis and drug‐induced hypersensitivity syndrome, are rare and occasionally fatal. However, it is difficult to detect SCARs at the drug development stage, necessitating a new approach for prediction. Th...

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Detalles Bibliográficos
Autores principales: Ambe, Kaori, Ohya, Kazuyuki, Takada, Waki, Suzuki, Masaharu, Tohkin, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993315/
https://www.ncbi.nlm.nih.gov/pubmed/33417306
http://dx.doi.org/10.1111/cts.12944