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In Silico Approach to Predict Severe Cutaneous Adverse Reactions Using the Japanese Adverse Drug Event Report Database
Severe cutaneous adverse reactions (SCARs), such as Stevens–Johnson syndrome/toxic epidermal necrolysis and drug‐induced hypersensitivity syndrome, are rare and occasionally fatal. However, it is difficult to detect SCARs at the drug development stage, necessitating a new approach for prediction. Th...
Autores principales: | Ambe, Kaori, Ohya, Kazuyuki, Takada, Waki, Suzuki, Masaharu, Tohkin, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993315/ https://www.ncbi.nlm.nih.gov/pubmed/33417306 http://dx.doi.org/10.1111/cts.12944 |
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