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Human Induced Pluripotent Stem Cell Derived Sensory Neurons are Sensitive to the Neurotoxic Effects of Paclitaxel

Chemotherapy‐induced peripheral neuropathy (CIPN) is a dose‐limiting adverse event associated with treatment with paclitaxel and other chemotherapeutic agents. The prevention and treatment of CIPN are limited by a lack of understanding of the molecular mechanisms underlying this toxicity. In the cur...

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Detalles Bibliográficos
Autores principales: Xiong, Chenling, Chua, Katherina C., Stage, Tore B., Priotti, Josefina, Kim, Jeffrey, Altman‐Merino, Anne, Chan, Daniel, Saraf, Krishna, Canato Ferracini, Amanda, Fattahi, Faranak, Kroetz, Deanna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993321/
https://www.ncbi.nlm.nih.gov/pubmed/33340242
http://dx.doi.org/10.1111/cts.12912