MYC oncogene is associated with suppression of tumor immunity and targeting Myc induces tumor cell immunogenicity for therapeutic whole cell vaccination

BACKGROUND: MYC oncogene is deregulated in 70% of all human cancers and is associated with multiple oncogenic functions including immunosuppression in the tumor microenvironment. The role of MYC in the immune microenvironment of neuroblastoma and melanoma is investigated and the effect of targeting...

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Detalles Bibliográficos
Autores principales: Wu, Xiaofang, Nelson, Marie, Basu, Mousumi, Srinivasan, Priya, Lazarski, Christopher, Zhang, Peng, Zheng, Pan, Sandler, Anthony David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993333/
https://www.ncbi.nlm.nih.gov/pubmed/33757986
http://dx.doi.org/10.1136/jitc-2020-001388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993333/
https://www.ncbi.nlm.nih.gov/pubmed/33757986
http://dx.doi.org/10.1136/jitc-2020-001388

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