Inhibition of bacterial and human zinc-metalloproteases by bisphosphonate- and catechol-containing compounds

Compounds containg catechol or bisphosphonate were tested as inhibitors of the zinc metalloproteases, thermolysin (TLN), pseudolysin (PLN) and aureolysin (ALN) which are bacterial virulence factors, and the human matrix metalloproteases MMP-9 and −14. Inhibition of virulence is a putative strategy i...

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Detalles Bibliográficos
Autores principales: Rahman, Fatema, Nguyen, Tra-Mi, Adekoya, Olayiwola A, Campestre, Cristina, Tortorella, Paolo, Sylte, Ingebrigt, Winberg, Jan-Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993378/
https://www.ncbi.nlm.nih.gov/pubmed/33757387
http://dx.doi.org/10.1080/14756366.2021.1901088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993378/
https://www.ncbi.nlm.nih.gov/pubmed/33757387
http://dx.doi.org/10.1080/14756366.2021.1901088

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