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Inhibition of bacterial and human zinc-metalloproteases by bisphosphonate- and catechol-containing compounds
Compounds containg catechol or bisphosphonate were tested as inhibitors of the zinc metalloproteases, thermolysin (TLN), pseudolysin (PLN) and aureolysin (ALN) which are bacterial virulence factors, and the human matrix metalloproteases MMP-9 and −14. Inhibition of virulence is a putative strategy i...
Autores principales: | Rahman, Fatema, Nguyen, Tra-Mi, Adekoya, Olayiwola A, Campestre, Cristina, Tortorella, Paolo, Sylte, Ingebrigt, Winberg, Jan-Olof |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993378/ https://www.ncbi.nlm.nih.gov/pubmed/33757387 http://dx.doi.org/10.1080/14756366.2021.1901088 |
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