Onopordopicrin from the new genus Shangwua as a novel thioredoxin reductase inhibitor to induce oxidative stress-mediated tumor cell apoptosis

Isolation and identification of natural products from plants is an essential approach for discovering drug candidates. Herein we report the characterization of three sesquiterpene lactones from a new genus Shangwua, e.g. onopordopicrin (ONP), C2, and C3, and evaluation of their pharmacological funct...

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Detalles Bibliográficos
Autores principales: Zhang, Junmin, Zheng, Zai-Qin, Xu, Qianhe, Li, Ya, Gao, Kun, Fang, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993383/
https://www.ncbi.nlm.nih.gov/pubmed/33733960
http://dx.doi.org/10.1080/14756366.2021.1899169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993383/
https://www.ncbi.nlm.nih.gov/pubmed/33733960
http://dx.doi.org/10.1080/14756366.2021.1899169

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