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Onopordopicrin from the new genus Shangwua as a novel thioredoxin reductase inhibitor to induce oxidative stress-mediated tumor cell apoptosis
Isolation and identification of natural products from plants is an essential approach for discovering drug candidates. Herein we report the characterization of three sesquiterpene lactones from a new genus Shangwua, e.g. onopordopicrin (ONP), C2, and C3, and evaluation of their pharmacological funct...
Autores principales: | Zhang, Junmin, Zheng, Zai-Qin, Xu, Qianhe, Li, Ya, Gao, Kun, Fang, Jianguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993383/ https://www.ncbi.nlm.nih.gov/pubmed/33733960 http://dx.doi.org/10.1080/14756366.2021.1899169 |
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