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The preclinical inhibitor GS441524 in combination with GC376 efficaciously inhibited the proliferation of SARS-CoV-2 in the mouse respiratory tract

The unprecedented coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a serious threat to global public health. Development of effective therapies against SARS-CoV-2 is urgently needed. Here, we evaluated the antiviral activity of...

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Detalles Bibliográficos
Autores principales: Shi, Yuejun, Shuai, Lei, Wen, Zhiyuan, Wang, Chong, Yan, Yuanyuan, Jiao, Zhe, Guo, Fenglin, Fu, Zhen F., Chen, Huanchun, Bu, Zhigao, Peng, Guiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993387/
https://www.ncbi.nlm.nih.gov/pubmed/33691601
http://dx.doi.org/10.1080/22221751.2021.1899770