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Spatial mapping of single cells in the Drosophila embryo from transcriptomic data based on topological consistency

The advancement in single-cell RNA sequencing technologies allow us to obtain transcriptome at single cell resolution. However, the original spatial context of cells, a crucial knowledge for understanding cellular and tissue-level functions, is often lost during sequencing. To address this issue, th...

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Detalles Bibliográficos
Autores principales: Zand, Maryam, Ruan, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993407/
https://www.ncbi.nlm.nih.gov/pubmed/33824719
http://dx.doi.org/10.12688/f1000research.24163.2