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Ammonia induced microglia activation was associated with limited effects on connexin 43 and aquaporin 4 expression in an astrocyte-microglia co-culture model

BACKGROUND: Hepatic encephalopathy (HE) is a neurological complication resulting from acute or chronic liver disease. Hyperammonemia leading to astrocyte swelling and cerebral edema in combination with neuroinflammation including microglia activation, mainly contribute to the pathogenesis of HE. How...

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Detalles Bibliográficos
Autores principales: Ismail, Fatme Seval, Faustmann, Timo Jendrik, Corvace, Franco, Tsvetanova, Anamariya, Moinfar, Zahra, Faustmann, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993489/
https://www.ncbi.nlm.nih.gov/pubmed/33765917
http://dx.doi.org/10.1186/s12868-021-00628-1