Cargando…

Nicardipine sensitizes temozolomide by inhibiting autophagy and promoting cell apoptosis in glioma stem cells

Glioblastoma multiforme (GBM) is the most invasive malignant central nervous system tumor with poor prognosis. Nicardipine, a dihydropyridine calcium channel antagonist, has been used as an adjuvant to enhance sensitivity to chemotherapeutic drugs. However, whether glioma stem cells (GSCs) can be se...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Jia, Dong, Xuchen, Li, Haoran, Wang, Haiyang, Jiang, Qianqian, Liu, Liang, Wang, Liping, Dong, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993688/
https://www.ncbi.nlm.nih.gov/pubmed/33621205
http://dx.doi.org/10.18632/aging.202539