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Nicardipine sensitizes temozolomide by inhibiting autophagy and promoting cell apoptosis in glioma stem cells
Glioblastoma multiforme (GBM) is the most invasive malignant central nervous system tumor with poor prognosis. Nicardipine, a dihydropyridine calcium channel antagonist, has been used as an adjuvant to enhance sensitivity to chemotherapeutic drugs. However, whether glioma stem cells (GSCs) can be se...
Autores principales: | Shi, Jia, Dong, Xuchen, Li, Haoran, Wang, Haiyang, Jiang, Qianqian, Liu, Liang, Wang, Liping, Dong, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993688/ https://www.ncbi.nlm.nih.gov/pubmed/33621205 http://dx.doi.org/10.18632/aging.202539 |
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