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In vitro P38MAPK inhibition in aged astrocytes decreases reactive astrocytes, inflammation and increases nutritive capacity after oxygen-glucose deprivation

Proper astroglial functioning is essential for the development and survival of neurons and oligodendroglia under physiologic and pathological circumstances. Indeed, malfunctioning of astrocytes represents an important factor contributing to brain injury. However, the molecular pathways of this astro...

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Detalles Bibliográficos
Autores principales: Revuelta, Miren, Elicegui, Amaia, Scheuer, Till, Endesfelder, Stefanie, Bührer, Christoph, Moreno-Cugnon, Leire, Matheu, Ander, Schmitz, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993689/
https://www.ncbi.nlm.nih.gov/pubmed/33563843
http://dx.doi.org/10.18632/aging.202651