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Levodopa affects spike and local field synchronisation in the pedunculopontine nucleus of a rat model of Parkinson’s disease

The pedunculopontine nucleus (PPN) undergoes significant anatomic and electrophysiological alterations in Parkinson’s disease (PD), severely impacting locomotion. However, the effect of 6-hydroxydopamine (6-OHDA) lesion and levodopa (L-DOPA) therapy on the relationships between spike activities and...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Xie, Jinlu, Li, Yaqiong, Liu, Huimin, Liu, Chuanguo, Kan, Dongfang, Geng, Xiwen, Wei, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993725/
https://www.ncbi.nlm.nih.gov/pubmed/33639616
http://dx.doi.org/10.18632/aging.202585