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Clusterin overexpression in mice exacerbates diabetic phenotypes but suppresses tumor progression in a mouse melanoma model

Clusterin (CLU) is an ATP-independent small heat shock protein-like chaperone, which functions both intra- and extra-cellularly. Consequently, it has been functionally involved in several physiological (including aging), as well as in pathological conditions and most age-related diseases, e.g., canc...

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Detalles Bibliográficos
Autores principales: Cheimonidi, Christina, Grivas, Ioannis N., Sesti, Fabiola, Kavrochorianou, Nadia, Gianniou, Despoina D., Taoufik, Era, Badounas, Fotis, Papassideri, Issidora, Rizzi, Federica, Tsitsilonis, Ourania E., Haralambous, Sylva, Trougakos, Ioannis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993736/
https://www.ncbi.nlm.nih.gov/pubmed/33744871
http://dx.doi.org/10.18632/aging.202788