MiR-506 exerts antineoplastic effects on osteosarcoma cells via inhibition of the Skp2 oncoprotein

S-phase kinase-associated protein 2 (Skp2) performs oncogenic functions in cancers; however, how Skp2 is regulated post-transcriptionally is elusive in osteosarcoma. Therefore, we determined whether miR-506 could directly target Skp2 in osteosarcoma to perform its tumor suppressive functions. Here,...

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Detalles Bibliográficos
Autores principales: Ding, Lu, Sun, Rongxin, Yan, Qi, Wang, Chengwei, Han, Xiaoping, Cui, Yong, Li, Rong, Liu, Jiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993745/
https://www.ncbi.nlm.nih.gov/pubmed/33621206
http://dx.doi.org/10.18632/aging.202530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993745/
https://www.ncbi.nlm.nih.gov/pubmed/33621206
http://dx.doi.org/10.18632/aging.202530

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