Deletion of a Golgi protein in Trypanosoma cruzi reveals a critical role for Mn(2+) in protein glycosylation needed for host cell invasion and intracellular replication

Trypanosoma cruzi is a protist parasite and the causative agent of American trypanosomiasis or Chagas disease. The parasite life cycle in its mammalian host includes an intracellular stage, and glycosylated proteins play a key role in host-parasite interaction facilitating adhesion, invasion and imm...

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Detalles Bibliográficos
Autores principales: Ramakrishnan, Srinivasan, Unger, Linn M., Baptista, Rodrigo P., Cruz-Bustos, Teresa, Docampo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993795/
https://www.ncbi.nlm.nih.gov/pubmed/33720977
http://dx.doi.org/10.1371/journal.ppat.1009399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993795/
https://www.ncbi.nlm.nih.gov/pubmed/33720977
http://dx.doi.org/10.1371/journal.ppat.1009399

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