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Robustification of RosettaAntibody and Rosetta SnugDock

In recent years, the observed antibody sequence space has grown exponentially due to advances in high-throughput sequencing of immune receptors. The rise in sequences has not been mirrored by a rise in structures, as experimental structure determination techniques have remained low-throughput. Compu...

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Detalles Bibliográficos
Autores principales: Jeliazkov, Jeliazko R., Frick, Rahel, Zhou, Jing, Gray, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993800/
https://www.ncbi.nlm.nih.gov/pubmed/33764990
http://dx.doi.org/10.1371/journal.pone.0234282